The natural history of chronic hepatitis B virus (HBV) infection is driven by complex interactions among virological, host, ...

The liver is responsible for more than 500 functions in the human body, including filtering harmful substances from the blood ...

Explore how CRISPR could become a powerful antiviral tool against HIV, Hepatitis B, HPV, and more, based on emerging research.

Current therapies for chronic hepatitis B virus (HBV) infection can effectively suppress viral replication but do not achieve a functional or complete cure. Capsid assembly modulators inhibit the ...

Ongoing clinical studies for four candidates on track with data expected in 2025, including interim Phase 1b data for long-acting helicase-primase inhibitors ABI-5366 and ABI-1179 anticipated in fall ...

Ongoing clinical studies for four candidates on track with data expected in 2025, including interim Phase 1b data for long-acting helicase-primase inhibitors ABI-5366 and ABI-1179 anticipated in fall ...

Additionally, in vitro data presented for ABI-4334 provide further insights into the potential for next-generation capsid assembly ... candidate for hepatitis D virus (HDV) infection The late ...

Additionally, in vitro data presented for ABI-4334 provide further insights into the potential for next-generation capsid assembly modulators to ... ABI-6250 specifically inhibits both HDV and ...

The company is dedicated to educating patients, providers, and others on new findings in chronic hepatitis B virus (HBV ... and molecules targeting the viral capsid, which results in inhibition ...

and efficacy results from participants with chronic hepatitis B virus (HBV) infection in its ongoing Phase 1b study evaluating ABI-4334, an investigational next-generation capsid assembly modulator ...

One approach to controlling assembly would be through the use of assembly inhibitors. Here we use Cp149, the assembly domain of the hepatitis B virus capsid protein, together with an assembly ...