whereas the DKK1-treated mouse group exhibited significantly reduced fibrosis. Conclusion: The Wnt signaling pathway plays a key role in the development of hepatic fibrosis associated with AE ...

This study investigates the potential involvement of mutations in the IL-36 receptor antagonist (IL36RN, IL-36RA) in the ...

The hormone works primarily by signaling the brain to improve ... Secret Boss of the Liver: Star-Shaped Cells That Promote Fibrosis Also Regulate Liver Health Mar. 12, 2025 — New research ...

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes ...

Robust broad-spectrum efficacy sustained over 1-year across all symptom domains including negative symptoms - - Generally ...

Pulmonary fibrosis encompasses a spectrum of interstitial lung diseases (ILDs) characterized by chronic inflammation, aberrant tissue remodeling, and ...

“Grade 2 fatty liver disease” is the term for moderate fatty liver disease and its symptoms. Fatty liver disease results from excessive buildup of fat in the liver. Medical professionals may ...

Despite the Middle East and North Africa having the highest global burden of metabolic dysfunction-associated steatotic liver disease, patients from this region remain markedly under-represented ...

Growth factor signalling is a cell signalling pathway that regulates the growth ... They reveal a synergistic MEK-JNK signaling response in colorectal cancer cells, suggesting a potential ...