These events are associated with innate training and can have long-term impacts on hematopoietic stem and progenitor cell (HSPC) development but can also compromise their function. While many ...

NEW YORK – In cell and gene therapies, the genetic machinery is key to producing the proteins missing or dysregulated in a disease, but whether the therapeutic cassette reaches target cells and how ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

Tumor-infiltrating clonal hematopoiesis (TI-CH) increased the risk of disease recurrence or death among patients with early ...

as well as cell lineage (i.e. somatic mtDNA and nuclear mutations). In addition to resolving the functional heterogeneity of immune cells throughout the body, we hope to help translate our basic ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

Under physiological conditions, mature hematopoietic cells freely circulate in the peripheral blood, while immature hematopoietic stem and progenitor cells (HSPCs) mostly reside in unique ...

NEW YORK – Researchers have developed a blood-based test for predicting whether non-Hodgkin lymphoma patients will respond to autologous CAR T-cell therapy prior to ... cell engager therapy or give ...