Scientists have discovered how aging blood stem cells acquire mutations that give them a growth edge, creating fertile ground for the development of clonol hematopoiesis, a condition that dramatically ...

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations.

This phenomenon, known as clonal hematopoiesis (CH), is a natural ... role of erythropoietin (EPO), a hormone that stimulates ...

Red blood cells carry oxygen from the lungs to every ... "We think these HSCs could be a reservoir of hematopoiesis in a ...

The cells with frequent donor-associated mutations functioned normally and promoted red blood cell production without ... Donato E, et al. Clonal hematopoiesis landscape in frequent blood donors.

Hematopoietic stem cells (HSCs) are multipotent progenitor cells found in the blood and bone marrow. They have the ability to self-renew, and during bone marrow hematopoiesis, HSCs differentiate into ...

Haematopoietic stem cells ... blood cells, including those of the myeloid and lymphoid lineages, and to replace themselves. In adults, they mainly reside in the bone marrow. We show that ...

A recent study in zebrafish presents a potentially important new system for studying the process of stem cell biology and hematopoiesis, the process by which blood is produced. The zebrafish has ...