For researchers working with prokaryotes it is now 1998. Bacteria do not have a directly homologous RNAi machinery, and targeted modification of gene expression is thus not easily possible.

The rise of VRE through the 1990s focused our attention on how natural product antibiotic scaffolds such as those of vancomycin and the related teicoplanin were assembled, 29, 30 in part to ...

Here we will consider the cell surface to include the lipid bilayer and the associated components that face the extracellular medium and form the glycocalyx (also known as the cell coat or the surface ...

Proteoglycans are a ubiquitous family of heavily glycosylated molecules consisting of a core protein with one or multiple covalently-attached linear anionic glycosaminoglycan (GAG) chains. The ...

† Department of Geochemistry, Geological Survey of Denmark and Greenland, Ø. Voldgade 10, DK-1350 Copenhagen, Denmark ‡ Department of Biology, Copenhagen University, Universitetsparken 15, DK-2100 ...

Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the United States and many developed nations. Two major age-related arterial phenotypes, large elastic artery ...

The NCBI Prokaryotic Genome Annotation Pipeline is designed to annotate bacterial and archaeal genomes (chromosomes and plasmids). Genome annotation is a multi-level process that includes prediction ...