However, it is likely that blocking any of the various astrocytic release pathways for glutamate, ATP and D-serine would be protective during ischemia. Perhaps fortuitously, many of the release ...

Serine and glutamate can be then employed for GSH synthesis ... These findings implicate p73 in regulation of cancer metabolism and suggest that TAp73 influences glutamine and serine metabolism ...

A link between macular telangiectasia type 2 and altered serine metabolism has been established previously. Through exome sequence analysis of a patient with macular telangiectasia type 2 and his ...

Monocytes then travel to the liver and along the way become macrophages – also immune cells. The presence of glutamate reprogrammes the metabolism of macrophages, and these consequently begin to ...

Identifying and targeting the mechanisms that increase glutamate metabolism in the brain may also provide the medical field with additional ways of treating problems within the brain. How the ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window A defect in serine metabolism was found to be behind a rare macular disease, according to researchers reporting a new ...

Star cells in the brain render memory flexible. Hippocampal astrocytes co-release D-serine and glutamate for the regulation of synaptic plasticity and cognitive flexibility. "The measure of ...

In order to be activated, NMDA receptors require the simultaneous presence of glutamate and the amino acids glycine or serine, which act as co-agonists. Knowing that glycine also acts on other ...