Panelists discuss how patients with immunoglobulin A (IgA) nephropathy typically present with microscopic or gross hematuria, often during upper respiratory infections, along with variable proteinuria ...

All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the ...

IgA nephropathy (IgAN) is characterized by the deposition of IgA1-containing immune complexes in the glomerular mesangium. The pathogenesis follows a 4-hit cascade: ...

Department of General Surgery, Tianjin Union Medical Center, Tianjin 300122, P. R. China These authors contributed equally to this work.

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada (C.S., K.J.R). Centre for Infection, Immunity ...

Pathophysiology, current treatments, and future directions. Journal of Medicinal and Pharmaceutical Chemistry Research, 2024, 6(7), 944-952 Joyce C. Hollander-Rodriguez and James F. Calvert.

Nausea is a common occurrence for people with diabetes. In some cases, it could be a sign of a life threatening condition that requires swift medical attention. Nausea can take many forms ...

Diabetes can affect any part of the digestive system. Over time, persistently high blood sugar levels can lead to damage that results in a range of symptoms, including diarrhea in some cases. It ...

The investigators found differential CK4 expression in the bladder walls vs trigone/urethra suggesting different pathogenesis. Positive CK4 expression occurred in the trigone and prostatic urethra ...

Diabetic nephropathy is the leading cause of kidney disease in patients starting renal replacement therapy and affects ~40% of type 1 and type 2 diabetic patients. It increases the risk of death ...

Renal histology reveals focal segmental glomerulosclerosis (FSGS), minimal change nephrotic syndrome (MCNS) and mesangioproliferative glomerulonephritis ... the related pathogenesis has been ...

Animals were maintained according to National Institutes of Health Guide for the Care and Use of Laboratory Animals with approval from the Institutional Animal Care and Use Committee of Nationwide ...