More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with ...

Knocking out a gene linked to brain circuitry leads to several hallmark behaviors of autism, a new study has found.

Radiation therapy can promote the epidermal growth factor receptor (EGFR) ligand amphiregulin, which increases growth of ...

A gene called astrotacton 2 (ASTN2) is one ASD-associated gene that was identified several years ago. Mutations in this gene can impair neurocircuits in the cerebellum of some ASD patients. New ...

Absence of cysteine in mice coaxed fat-storing cells to burn energy, causing weight loss and offering potential therapeutic ...

Mice with the Tob gene showed increased levels of the Tob protein in response to stress. The Tob knockout mice showed signs of fear, anxiety and depression in their behavior.

We were trying to learn how certain animals lost their regeneration capacity during evolution and then put back the ...

Gene knockout mice exist for about 75% of the corresponding genes in the human genome, Lloyd said. The new KOMP2 awards and collaborative efforts by other IMPC members over the next five years will ...

Mitochondria possess their own DNA (mtDNA), which plays important roles in cellular respiration and energy consumption.

Without both doses, gene expression can go awry, and the resulting embryos can end up with abnormalities. This is what researchers have found in previous attempts to create mice with two dads.

Now the same lab has found that knocking out the gene entirely leads to several hallmark behaviors of autism. As they describe in a new paper in PNAS, mice that lacked ASTN2 showed distinctly ...