Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

A research group led by Wei Li at the Chinese Academy of Sciences has created mice born from two male parents and capable of ...

Many foods are often advertised for their antioxidant properties. Antioxidants counteract what are known as reactive oxygen ...

A gene-edited mouse with two male parents has survived to adulthood, pushing new progress on stem cell research.

For those frustrated by the brute force of knockout mice when studying gene function, in vivo RNA interference (RNAi) would seem to have come to the rescue. In theory, in vivo RNAi promises a more ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

They followed by isolating EVs from normal mice and knockout mice lacking the gene that encodes the BK potassium channel, and found the cargo in EVs from the knockout mice were very different in ...

Both gene knockout and knock-in models are powerful tools widely used in biomedical research to gain important insights into ...

Researchers say study represents a resource that could also help to dissect Y-gene functions in other tissues.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...