CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

Radiation therapy can promote the epidermal growth factor receptor (EGFR) ligand amphiregulin, which increases growth of ...

One of the biggest obstacles in cancer treatment is drug resistance in cancer cells. Conventional efforts have focused on ...

UFC Atlanta, headlined by the welterweight return of former champion Kamaru Usman, taking on Joaquin Buckley, kicked off to a good start, with Cameron Wellmaker scoring an amazing knockout over ...

Gene knockdown: an experimental technique which inhibits the expression of one or more of an organism's genes. It is different than gene knockout, which inactivates or removes the gene completely.

Intellia is utilizing this gene knockout approach to remove unwanted proteins using its proprietary lipid nanoparticle delivery system.

Gene Deal, Diddy’s former bodyguard, was banned from the rapper’s trial after allegedly knocking out a YouTuber outside a NYC courthouse.

References 1. Porreca I. et al. An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation.

Through knock-out experiments in mice they showed that SRY, via an “enhancer” gene, activates another gene called SOX9, which ultimately drives the development of the testes.

Researchers used mitochondrial gene editing to model genetic disorders in mice, revealing profound impacts on brain function, metabolism, and thermoregulation.

This study investigates the impact of sodium channel protein type 1 subunit alpha (SCN1A) gene knockout (SCN1A KO) on brain development and function using cerebral organoids coupled with a multiomics ...

A gene called astrotacton 2 (ASTN2) is one ASD-associated gene that was identified several years ago. Mutations in this gene can impair neurocircuits in the cerebellum of some ASD patients. New ...