What if we could reprogramme the TME itself? Cutting-edge research suggests that engineered mesenchymal stem cells (MSCs) could disrupt this shield – targeting tumours in a way that finally ...

In March 2025, the European Patent Office issued a Notice of Allowance for a new patent application (European Patent Appl. No. 20798130.9) covering key aspects of BioRestorative’s allogeneic, ...

Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological ...

Get Instant Summarized Text (Gist) A stem cell-derived 3D model replicates human amniotic sac development from two to four weeks post-fertilization, closely matching the structure and function of ...

As the field of engineered ex vivo cell therapies ... has expanded dramatically. While T cells remain the most common starting material, Mancini noted that “natural killer (NK) cells and induced ...

This is the first gene editor to use a CRISPR-associated transposase to make targeted edits at therapeutically useful levels ...

One of the most commonly used gene-delivery methods relies on engineered viruses to insert stretches of genetic material into ...

Scientists at the McGovern Institute and the Broad Institute of MIT and Harvard have reengineered a compact RNA-guided enzyme ...

Biomedical engineers at Georgia Tech created a treatment that could one day unlock a universal strategy for treating some of ...

The UNC technology, developed by Pediatrics Professor Chengwen Li, M.D., Ph.D., uses adeno-associated viruses (AAVs) to ferry ...