Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study ...

Proteins interacting with cell membranes play a vital role in countless biological processes, from how cells communicate to ...

G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

Previously unknown access points in cell membrane proteins have been discovered, enabling laboratory-developed drugs to modify cell function. The discovery was made possible through computer ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

This study employed high-throughput screening and animal models to identify FPR2, a G protein-coupled receptor (GPCR) expressed at the adipocyte plasma membrane, as a critical ceramide receptor. This ...

GPCRs are the largest family of proteins found in the membranes of cells and are thought to be involved in almost all physiological processes within the body. They are a common target for drug ...

Key GPCR family receptors that are related to diseases. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or ...

Researchers were able to observe, at atomic scale and in real time, how membrane lipids interact with G protein-coupled receptors (GPCRs) in their natural environment. These interactions reveal ...