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A novel chemical probe identification platform was created in which GPCR-focused libraries were screened against sets of oGPCR targets, with a goal of discovering fit-for-purpose chemical probes for ...

5 One patient with SFN associated with antibodies against G Protein-Coupled Receptors (GPCR) and FGF Receptor-3 (FGFR3) after the first dose of BNT162b2 has not yet been reported. The patient is a ...

Collaboration combines Novo Nordisk’s scientific leadership in obesity and cardiometabolic diseases with Septerna’s expertise in G protein-coupled receptor (GPCR) drug discovery Goal is to ...

Collaboration combines Novo Nordisk’s scientific leadership in obesity and cardiometabolic diseases with Septerna’s expertise in G protein-coupled receptor (GPCR) drug discovery Goal is to develop ...

ABCL635 targets neurokinin 3 receptor or NK3R, which is a GPCR involved in endocrine homeostasis and thermoregulation. Notably, ABCL635 is the first program from our GPCR and ion channels platform ...

本文聚焦 G 蛋白偶联受体（GPCR）与离子通道间的相互作用。详细阐述了二者在膜垂直和水平方向的信号转导机制，分析了相关复合物的结构基础，探讨了研究面临的挑战及技术进展，为理解细胞 ...

Heterotrimeric G proteins act as molecular switches that control cellular responses to external signals. Small molecules that selectively inhibit these proteins are essential for studying their ...

Dublin, May 06, 2025 (GLOBE NEWSWIRE) -- The "G-Protein Coupled Receptor (GPCR) Targeting: Technologies and Global Markets" report has been added to ResearchAndMarkets.com's offering. The global G ...

Solid-state NMR spectra with single-site resolution of CXCR1, a G protein-coupled receptor (GPCR), were obtained in magnetically aligned phospholipid bicelles. These results demonstrate that GPCRs in ...

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 2, 2025, titled "Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK ...