Given the known benefits of heart rate reduction for cardiac disease, coupled with the intolerability of current options in many patients, ivabradine may be a significant addition to the ...

Targeted heart rate control using the funny current inhibitor ivabradine to reduce morbidity in patients undergoing non-cardiac surgery: a phase IIa, triple blind, placebo controlled randomised trial ...

The slower heart rate isn’t as funny — it has fewer funny channels to transmit current that controls the activity of the heart cells. The results suggest a mechanism for sinus bradycardia in ...