Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases in mouse ...

For example, T cells can be identified using fluorescently labelled antibodies specific for the CD3 cell-surface marker and either the CD4 or CD8 cell-surface markers (two-colour flow cytometry).

A new study in Small presents a nanoparticle-based delivery system combining CuET and BIO for treating resistant melanoma, ...

Here the authors use both patient data and a mouse glomerulonephritis model to show that increased type I interferon may expand a subset of pro-inflammatory T cells for subsequent kidney pathology.

Method reveals unexpected behavior in molecular crowding during cell state transitions and suggests density as a biomarker for functional precision medicine.

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Measuring the density of a cell can reveal a great deal about the cell's state. As cells proliferate, differentiate, or ...

Cells are the smallest units of life. But even within the same tissue or organ, they are not all identical. New variations arise continuously during cell proliferation. While genetic mutations alter ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

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NEW YORK – PeproMene Bio will expand the ongoing Phase I PMB-102 study of its BAFF-R-targeted CAR T-cell therapy PMB-CT01 after showing initial efficacy in seven lymphoma patients, the firm said ...