Extrachromosomal DNAs (ecDNAs) encode oncogenic driver proteins, regulatory elements, immunomodulators, and genes of yet-unknown oncogenicity (Panel A). They exist as circular pieces of DNA in the ...

Thus, they are referred to as extrachromosomal circular DNA. But scientists still know relatively little about their function, mainly because they have lacked technologies for a more detailed ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes ...

It is for this reason that they are referred to as extrachromosomal circular DNA. But even nowadays, scientists know relatively little about their function, mainly because they have lacked ...

These circles, now known as extrachromosomal DNA (ecDNA), may ... Without centromeres, a cell has no way to nicely divvy up circular DNA between its progeny, and the circles are dispersed at ...

Now, researchers from UC San Diego and their colleagues have found that HPV DNA hybridizes with human DNA genes in oropharyngeal cancer cells, forming extrachromosomal circular DNA (ecDNA) that ...

the extrachromosomal DNA (ecDNA) found in some cancer cells is not always split evenly. Lacking centromeres, these circular bits of DNA are often unevenly parceled to daughter cells. Some daughter ...

But another population of DNA, called extrachromosomal circular DNA, is shaped like a circle, with no loose ends, and exists independently of linear DNA. While researchers are beginning to better ...

EcDNA is made up of small, circular segments of DNA that form outside of chromosomes within the cell, and is frequently found in cancer cells. It has been shown to elude the immune system and ...