Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes ...

Scientists have now learned more about a process in which the genome of HPV links to human genes in cancer cells of oropharyngeal tumors; this leads to the formation of extrachromosomal circular DNA ...

EcDNA is made up of small, circular segments of DNA that form outside of chromosomes within the cell, and is frequently found in cancer cells. It has been shown to elude the immune system and ...

The human cell’s instruction manual, DNA, is mostly stored in packages called chromosomes. In 1965, researchers in the United States and the United Kingdom detected an enigmatic extrachromosomal ...

Extrachromosomal DNAs (ecDNAs) encode oncogenic driver proteins, regulatory elements, immunomodulators, and genes of yet-unknown oncogenicity (Panel A). They exist as circular pieces of DNA in the ...

How can DNA from a cheek swab determine if someone is closely related to you? When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. DNA tests can ...

Once brushed aside as a curiosity, extrachromosomal DNA (ecDNA) is now taking centrestage ... break away from the main chromosome and form a circular structure that floats freely inside the ...

shed light on the unique behaviour of extrachromosomal DNA (ecDNA), small, circular DNA structures that are common in some of the most difficult to treat cancers. The papers identify, for the ...

PMID: 32277852 Kumar P, Kiran S, Saha S, Su Z, Paulsen T, Chatrath A, Shibata Y, Shibata E, Dutta A, ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines., 2020; ...