Yeast has proven a valuable model system to understand eukaryotic transcription mechanisms. Extending the vale of the system even further, several investigators have attempted to express mammalian ...

Here we asked how genetic modifications shape the dose–response curve of biosensors based on metabolite-responsive transcription factors. Using the lac system in Escherichia coli as a model system, we ...

Transcription-coupled repair (TCR) — the fast, preferential repair of the transcribed strand of an active gene — occurs in both prokaryotes and eukaryotes. This kind of repair is performed by ...

To our knowledge, this is the first report conclusively identifying in vivo D/E-methylation substrates and their modification sites in eukaryotic cells, demonstrating that D/E-methylations are ...

While the endosymbiotic theory, which proposes that eukaryotic cells emerged from a fusion between ... becoming non-linear through the spliceosome and the nucleus, which separated transcription and ...

Their USP? Recording and transcription capabilities that make the capture of minutes during meetings a breeze. Now that I’ve experienced the possibility of listening to music one minute ...

Integrated transcriptomic analysis indicated that HIC1 might regulate VSMC phenotypic modulation by activating Jag1 (Jagged 1) transcription. Suv39h1 (suppressor of variegation 3-9 homolog 1) ...

This is an important study utilizing innovative CRISPR based approaches demonstrating the role of the KLF family of transcription factors in the post natal maturation of cortical projection neurons.