New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

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Enzymes catalyze cell reactions; coenzymes like CoQ10 are crucial for energy production and health, with potential genetic ...

Discover three evidence-based approaches that tackle the root causes of fatigue, delivering quick energy boosts and long-term ...

Although benzodiazepines like Valium and Xanas are often prescribed to treat mental health issues and inflammation-related diseases, Virginia Commonwealth University (VCU) researchers are ...

Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...

Cells can’t operate without the power supplied by working mitochondria ... thus leaving the enzyme’s tasks incomplete. PZL-A binds to an allosteric site on POLG that is conserved across ...

the perfect conditions were created for the potentially toxic algae to bloom from the depths where it has always been present. Image caption, The department said the algae blooms are "no surprise ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...

In this study, a mouse model with a knockout of the mitochondrial tRNA modification enzyme (Mto1) exhibited defective mitochondrial protein synthesis, revealing a previously unknown molecular ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...