Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

After precipitation and purification, the DNA was subjected to ChIP DNA sequencing (ChIP-seq) or real-time quantitative polymerase chain reaction (RT-qPCR) analysis as indicated in the figures. For ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

The scientists used cryo-electron microscopy to decipher the three-dimensional (3D) structure of the RNA polymerase. They shock-froze the RNA polymerase in two different states, free and bound to ...

The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions. By Gina Kolata Researchers have corrected a disease ...

Faculty of Physics and CeNS, Ludwig-Maximilians-Universität München, 80539 München, Germany Walter Schottky Institute, Technical University of Munich, 85748 München, Germany Physics Department, TUM ...

Scientists found that rapidly evolving DNA regions, known as human accelerated regions (HARs), help human neurons form complex networks, contributing to higher brain function but possibly increasing ...

Production of the enzyme itself involves a microorganism that’s been genetically engineered to include the DNA for making the enzyme and housed in a fermenter so it can replicate and churn out ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...

In this study, we unveil a common mechanism underlying these observations for the DNA-scaffolded enzymes that acts on enzymes independent of their catalytic mechanisms. By testing a variety of ...