Septic liver injury type: hypoxic hepatitis ... For example, the increase in ROS can lead to the activation of endothelial cells, promoting the expression of adhesion molecules and the recruitment of ...

William Hewes, aged 22, died within 24 hours of being admitted to Homerton University Hospital in January 2023 after his bacterial meningitis infection developed into sepsis. Medical staff failed ...

AURN001 is a combination cell therapy product candidate comprised of allogeneic human corneal endothelial cells (neltependocel) and a rho kinase inhibitor (Y-27632). This investigational product ...

Sepsis is one of the deadliest conditions in intensive care units (ICUs), triggered by the body's out-of-control response to infection. Despite medical advancements, its in-hospital mortality rate ...

The heartbroken family of a mum who died after medics failed to give her antibiotics to treat sepsis have spoken out about her devastating death. Hassan Naseer's wife Sharzia Bibi, 28, was ...

This state is mediated by a receptor on endothelial cells called Tie2. Under normal conditions, ANGPT2 prompts Tie2 to produce an anti-inflammatory response. However, these conditions are reversed ...

Endothelial cell inflammation causes vasodilation through ... Inflammation and coagulation are closely linked in sepsis. Inflammatory mediators generate tissue factor expression and initiate ...

Even subclinical changes in coagulation likely increase the risk of AF in septic patients. This suggests that more specific markers of coagulation may be required to better understand the role of ...

Vascular endothelial cells (vECs) in the brain exhibit structural and functional heterogeneity. Fenestrated, permeable brain vasculature mediates neuroendocrine function, body-fluid regulation, and ...