Sanofi and Johnson & Johnson ended development of an experimental vaccine after it failed to adequately protect against an ...

Salmonella and E. coli are well-known bacteria that cause ... rustigianii carries a cytolethal distending toxin virulence gene on its plasmid. Elimination of this gene did not reduce the ...

Pharmaceutical giants Johnson & Johnson and Sanofi have stopped a late-stage clinical trial for their experimental E.coli vaccine after results failed to demonstrate sufficient efficacy.

The chromosomal hha gene (high hemolysin activity) of E. coli was first identified in a search for mutants that overproduced the toxin, α-hemolysin, from a plasmid-encoded hemolytic hly operon of E.

To prepare the cloning vectors, transform separately pET11a-link-NGFP and pMRBAD-link-CGFP into an E. coli strain that gives high-quality plasmid DNA (for example, DH10B or XL1-Blue) and plate ...

Reporter genes are generally joined to a regulatory DNA sequence in an expression vector that is usually propagated in Escherichia coli before transfection into ... with the experimental reporter ...

Escherichia coli, commonly known as E. coli, is a versatile bacterium. While many strains are harmless and a natural part of our intestinal ...

Update on extraintestinal pathogenic E. coli vaccine phase 3 clinical studyIndependent interim analysis of the E.mbrace phase 3 study finds that ...