Since the discovery of penicillin nearly a century ago, antimicrobial resistance (AMR) has become a stealthy, pervasive enemy ...

We collaborate with the world's leading lawyers to deliver news tailored for you. Sign Up for any (or all) of our 25+ Newsletters. Some states have laws and ethical rules regarding solicitation ...

Meanwhile, Kariya is developing KP405, a first-in-class, dual GLP-1/GIP receptor agonist, initially for Parkinson’s disease with plans for a study in Alzheimer’s. Hölscher previously told BioSpace ...

Also, these receptors respond not just to bitter-tasting substances, but to various kinds of drugs. Consequently, the dual-binding mechanism found for TAS2R14 opens up new possibilities for drug ...

The screen identified a group drugs, including clemastine, that had one thing in common: they blocked muscarinic receptors. Clemastine’s benefits begin with its effect on oligodendrocyte precursor ...

July 3 (UPI) --U.S. researchers said Wednesday that they have identified a new drug that could ... of the opioid receptor, in part due to naloxone remaining in the binding pocket at least 10 ...

The selectivity for M3 receptors renders tiotropium its unique clinical advantages. Drugs such as tiotropium work well because of kinetic differences – however, they were not designed that way several ...

New work shows that these receptors produce different effects when they are inside or on the outside of neurons. This could guide design of new drugs based on psychedelics to treat mental illness.