A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake. Scientists had zeroed in ...

Researchers have identified two new drug families that block a key tuberculosis (TB) enzyme, offering hope for novel ...

While biopharmaceutical technologies have made substantial strides in treating diseases, drug research and development ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Molecular architecture of M. tuberculosis MmpL4. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-56888-6 ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

XtalPi has accrued a number of Big Pharma partners over the years, including Eli Lilly, which struck a $250 million deal in 2023 to use XtalPi’s tech to identify potential drug candidates that Lilly ...

EM, researchers elucidated the structure of key receptors integral to fast excitatory synaptic transmission in the rat ...

A new cancer drug candidate developed by Lawrence Livermore National Laboratory, BridgeBio Oncology Therapeutics and ...

Scientists have discovered how to turn molecules made by everyday toxic mold into highly effective cancer-fighting drugs.

Scientists mapped the bacterial flagellum in atomic detail, revealing it as a target to disarm infections without killing ...

The US Food and Drug Administration (FDA) has issued an urgent warning about tianeptine – a substance marketed as a dietary ...