A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake. Scientists had zeroed in ...

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections. To aid ...

Researchers have identified two new drug families that block a key tuberculosis (TB) enzyme, offering hope for novel ...

While biopharmaceutical technologies have made substantial strides in treating diseases, drug research and development ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

XtalPi has accrued a number of Big Pharma partners over the years, including Eli Lilly, which struck a $250 million deal in 2023 to use XtalPi’s tech to identify potential drug candidates that Lilly ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Scientists mapped the bacterial flagellum in atomic detail, revealing it as a target to disarm infections without killing ...

The US Food and Drug Administration (FDA) has issued an urgent warning about tianeptine – a substance marketed as a dietary ...

Both well-established and small, clinical-stage pharma companies are investing heavily to be able to someday compete with ...

Penn engineering researchers modified a fungus called Aspergillus flavus, which may have caused lung disease and illness in ...