Both lead optimization (the process by which a small organic molecule is refined ... for activities against drug targets), are greatly aided if the three-dimensional structure of the biological ...

Unraveling the molecular structure of the viral polymerase complex ... of the polymerase structure that could be leveraged as drug targets," said co-corresponding author Jonathan Abraham ...

the tool could potentially help chemists design new molecules and closely study how well their drug prototypes for cancer and other diseases would interact with the molecular structure it intends ...

Short chains of amino acids can form drug delivery nanoparticles and boost the properties of potential medicines ...

Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the ...

Molecular glues have emerged as one of the promising approaches for drug discovery to treat a wide range of diseases such as cancer, inflammatory and immune diseases, and infections. Currently, ...

identification assays and structure-based design. With numerous strategic collaborations and investments into rationale drug discovery, the molecular glue field is fuelling the clinical ...