SINGAPORE, 8 November 2018 - Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy.

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic ...

According to the Center for Disease Control, 1.25 million people suffer from type 1 diabetes in the US alone. So far, it can only be managed with diet and regular doses of insulin, but scientists ...

Heart organoids simulate pregestational diabetes-induced congenital heart disease Date: February 8, 2024 Source: Cell Press Summary: An advanced human heart organoid system can be used to model ...

Scientists prevent, reverse diabetes-related kidney destruction in animal model. ScienceDaily . Retrieved May 17, 2025 from www.sciencedaily.com / releases / 2015 / 12 / 151228161255.htm ...

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Researchers from Osaka Metropolitan University have identified a gene that, when activated by metabolic stress, damages ...

Diabetic mice grafted with non-vascularized SC-islets fared poorly compared to those grafted with vascularized SC-islet cells, with some mice showing no signs of the disease ... model to study ...

Crucially, C. dubliniensis exposure in early life also dramatically reduced the risk of type 1 diabetes for at-risk male mice. When male mice that were genetically predisposed to develop type 1 ...

More information: Yang Gou et al, AgRP neuron hyperactivity drives hyperglycemia in a mouse model of type 2 diabetes, Journal of Clinical Investigation (2025). DOI: 10.1172/JCI189842 Journal ...

Diabetic mice grafted with non-vascularized SC-islets fared poorly compared to those grafted with vascularized SC-islet cells, with some mice showing no signs of the disease ... model for diabetes ...