These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action. There are two main endocannabinoid receptors: CB1 receptors ...

It acts on more than 65 receptors in your brain, some of which affect your levels of serotonin. That’s a brain chemical that helps control your mood. Several drugs already used to treat anxiety ...

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

Get Instant Summarized Text (Gist) A 2016 bird flu variant was found to be one mutation away from binding to human receptors, highlighting the potential for avian influenza to adapt to humans. The ...

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a group of drugs used to treat type 2 diabetes and sometimes obesity. GLP-1 RAs are very effective at lowering blood sugar levels.

Many in the medical community believe there’s clear evidence that a fetus – a developing baby in the womb – can’t feel physical pain until after the 24th week (6th month) of pregnancy. But ...

2 University College London Hospitals NHS Foundation Trust, London, UK Background and aims Mineralocorticoid receptor antagonists (MRAs) reduce mortality and hospitalisation in heart failure with ...

Every soft caress of wind, searing burn and seismic rumble is detected by our skin’s tangle of touch sensors. David Ginty has spent his career cataloging the neurons beneath everyday sensations. Like ...

Pfizer Inc. (NYSE: PFE) today announced the decision to discontinue development of danuglipron (PF-06882961), an oral glucagon-like peptide-1 (GLP-1) receptor agonist, which was being investigated ...

This patent highlight describes a series of novel 2-pyrrolidone derivatives that act as negative allosteric modulators (NAMs) of GluN2B-containing N-methyl-d-aspartic acid receptors (NMDARs). These ...