Nucleotide-binding proteins are proteins that bind to nucleotides. For example, kinases bind adenosine triphosphate (ATP) and G proteins bind guanosine triphosphate (GTP). Other nucleotide-binding ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

Genetic mutations occur everyday in our cells, but the vast majority of them are repaired. New research finds DNA repair is not on PAR in HD cells, causing mutations to build up in people with HD.

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

The molecular pathways involved in antiviral defenses and counter-defenses in host-pathogen systems remain unclear. Researchers have used Neurospora crassa as a model organism to explore how RNA ...

Several genetic studies have attempted to explore the fungal factors involved in antiviral responses, but the exact genes and ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...