This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

Professor Anton GARTNER (Distinguished Professor at the UNIST Graduate School of Medicine and Associate Faculty of the IBS ...

Abstract Faithful chromosome segregation requires the removal of all DNA bridges physically linking chromatids before the completion of cell division ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Mass photometry enables rapid, purification-free quantification of rAAV vectors, offering a faster solution for gene therapy ...

Researchers demonstrated that specific electromagnetic wave frequencies can disrupt the SARS-CoV-2 Spike protein structure in ...

Prime Medicine is eliminating 25% of its workforce in a restructuring that includes the company pivoting its prime ...

Leading cancer researchers from UC San Francisco presented talks about advances in targeted therapies, cancer genomics, using AI to personalize cancer treatment, improving diagnosis of hard-to-treat ...

Reshma Bano is a postdoctoral research fellow at the Department of Physics, University of Surrey. She earned her PhD in ...

Our assay is based on the fully automated, time-resolved quantification of phospho-SER139-H2AX (γH2AX) and 53BP1 foci, two factors involved in the DNA damage response network, in cells treated with ...