This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

Abstract Faithful chromosome segregation requires the removal of all DNA bridges physically linking chromatids before the completion of cell division ...

Prime Medicine is eliminating 25% of its workforce in a restructuring that includes the company pivoting its prime ...

If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic ...

A recent study on the application of metagenomic next-generation sequencing (mNGS) found that mNGS can achieve early ...

Once the binding assay is developed, it can be used for various applications, including compound profiling, hit validation, fragment screening, mapping binding sites, and even thermodynamic studies.

Qiagen (NYSE:QGEN) announced a new commercial collaboration and joint marketing agreement with French company ID Solutions to ...

ID Solutions will produce and supply dPCR assays for use in non-clinical research on Qiagen's QIAcuity platforms.

Chemical modifications in DNA enable hidden messages for secure data transmission. Here, authors develop DeepSME, a nanopore sequencing and deep-learning framework that conceals data into DNA ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).