DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there ...

Eukaryotic cells form the foundation of complex ... For example, mutations in mitochondrial DNA can disrupt oxidative phosphorylation, leading to reduced ATP production and increased reactive oxygen ...

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

New research challenges the view that proteins are the only key to evolution, highlighting the importance of lipids.

An international team of microbiologists from the Medical University of Graz, the DSMZ—German Collection of Microorganisms ...

In the default model, the graph representing each individual enhancer can be arbitrarily complicated. To show how the ABC Score formula can arise from the default model, we need to impose the further ...

Investigators have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be formulated completely as ...

Prototaxites, an extinct organism from the Devonian period, has been thought to be a fungus since its first fossil was unearthed. Analysis of one Prototaxites species showed that its physical and ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without ...

Robert Hettich with new mass spectrometry instrumentation at ORNL. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy Robert ...