GEN talked with several contract development and manufacturing organizations (CDMOs) and/or contract research organizations (CROs) about new ways they are addressing AAV manufacturing challenges.

The presence or absence of 5′ phosphates on the linear vector ends made ... review by the E. coli replication machinery. Both of these advances present new options for DNA engineering.

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a ...

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through ...

Researchers demonstrated how Mycobacterium tuberculosis modifies its DNA and regulates both replication and gene activity ...

Cell division is an essential biological process that removes aged cells and continuously renews tissues. In the human body, billions of cells divide each day: intestinal cells are completely renewed ...

Researchers work in a mobile Fire-Eye laboratory in Beijing in June 2020. The labs can identify coronavirus infections, as well as decipher and analyze human DNA. (Fu Tian/China News Service/Getty ...