Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

The personalized CRISPR treatment could be the future of gene therapy, but hurdles remain before everyone has access.

Scientists have used personalised gene-editing therapy to successfully treat a baby with a rare genetic condition. Could this ...

Entire sections of the chromosome where the repair ... CRISPR's molecular scissors cannot distinguish between the different versions of the gene and therefore occasionally cut the DNA strand ...

The custom-built gene editing treatment for 6-month-old KJ Muldoon could not have come at a more welcome or jarring time for ...

Once a cut is made, it is a multistep, imperfect process of cellular DNA repair. CRISPR can be used to make other types of edits too, such as increasing or decreasing the effects of a gene ...

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate ...

introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, including off-target cutting. Over the years, scientists have ...

Crucially, unlike CRISPR, the system does all this without breaking strands of DNA or relying on the cell to repair them, a process that can be damaging and unpredictable. The various molecules ...