News

Hidden architecture: Researchers identify new molecular structure at center of chromosomes
Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...
C&EN14d
Analysis of Vascular Smooth Muscle Cells from Thoracic Aortic Aneurysms Reveals DNA Damage and Cell Cycle Arrest as Hallmarks in Bicuspid Aortic Valve Patients
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Article Views ...
The EMBO Journal15d
High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling
Iterations of AAVPureMfg are developed with new plasmid structure design and reduced plasmid demand. AAVPureMfg substantially improves rAAV product purity by mitigating prokaryotic DNA encapsidation ...
eLife17d
Modular DNA Barcoding of Nanobodies Enables Multiplexed in situ Protein Imaging and High-throughput Biomolecule Detection
The authors advance this technique by integrating peptide ligation technology and nanobody-based antibody mimetics - cost-effective and scalable alternatives to conventional antibodies - into a ...
News Medical18d
New insights into HIV-1 capsid disruption open doors for novel therapies
Announcing a new publication for Acta Materia Medica journal. The HIV-1 capsid protein (CA) plays a crucial role in viral replication by orchestrating nuclear entry through interactions with host ...
C&EN22d
Leveraging Protein–Ligand and DNA Interactions to Control Hydrogel Mechanics
Department of Materials Science and Engineering, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States International Institute for Nanotechnology, Northwestern ...