The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

AAV9 capsid ... The cryo-EM structure of phage φTE is presented, revealing a distinct neck topology, tail sheath baseplate organization and oligomeric state of the tape measure protein.

Researchers at UNIST and the Institute for Basic Science (IBS) have, for the first time, elucidated how a critical protein ... During division, DNA must be accurately duplicated and separated. However ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

Most proteins are left-handed, but scientists have found an ancient molecule that works in both mirror-image forms.

Huntington's disease is a genetic disorder that kills nerve cells in the brain, causing people to lose their cognitive and ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

In a study published in The EMBO Journal, researchers show how Mycobacterium tuberculosis uses a reversible process called ADP-ribosylation to modify its DNA and control both replication and gene ...

Announcing a new publication for Acta Materia Medica journal. The HIV-1 capsid protein (CA) plays a crucial role in viral replication by orchestrating nuclear entry through interactions with host ...

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread ...