Pancreatic cancer’s deadly resilience may be tied to extrachromosomal DNA, which allows tumor cells to rapidly adapt to ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems ...

Arthur Kornberg compared DNA to a tape recording of instructions that can be copied over and over. How do cells make these near-perfect copies, and does the process ever vary? In reality ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems ...

Once scientists have zeroed in on a specific segment of DNA, how do they produce enough copies of that segment for their research? In most cases, the polymerase chain reaction, or PCR, is their ...

Scientists suggest understanding ecDNA’s role in pancreatic cancer could potentially guide future strategies for making ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...

Determining the number of copies of a double stranded DNA template (be it genomic DNA, plasmid or an amplified fragment) is essential for many genetic quantification applications in research and ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.

Low copy number PCR 5 Low copy number PCR amplifies low amounts of DNA (typically <100-200pg). Increasing the number of amplification cycles to 34 instead of 28 helps increase sensitivity. Additional ...