When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation. In most vertebrates, the absence of adaptive immunity would be ...

The cancer vaccine targets the lymph system and enhances its ability to recruit T cells to eliminate tumors. Here, three T cells (blue) are shown attacking and breaking apart a cancer cell.

Ipilimumab, a cancer immunotherapy, reduced scar formation and promoted tissue regeneration in a mouse model of idiopathic ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

To avoid an overreactive response that harms healthy cells, cytotoxic T lymphocytes express inhibitory surface receptors, or immune checkpoint molecules. Tumors can avoid attack by binding to these ...

They also respond in different ways. Even T cells don’t just do one thing. Some – the cytotoxic T cells – attack infected cells directly, while others – the T helper cells – support immune responses ...

Dragonfly's TriNKET compounds are designed to activate and direct NK and cytotoxic T cell killing against cancer cells. The platform has also attracted partnerships from other pharma groups ...

Currently, there are six CAR T-cell therapy products approved by the US Food and Drug Administration (FDA), and more are expected to be approved in the next few years. Immune effector cells such as ...

and increased population frequency of CD8 + cytotoxic effector cells. Analyzing results from transcriptomic sequencing of T cells from three healthy donors, in the new data being presented today ...