Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre-Cebollada, has developed an ...

In this important study, the authors conducted atomistic molecular dynamics simulations to probe the interactions between IRE and unfolded peptides. The results help reconcile contradicting ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways ...

KPV peptide, a small bioactive tripeptide, has garnered increasing attention within various research domains due to its ...

A study by researchers at the Interuniversity Institute of Bioinformatics in Brussels, the Structural Biology research group at Vrije Universiteit Brussel, and IBiTech–BioMMedA Group of Ghent ...

We report that a GpA-TM peptide readily crystallized in a monoolein cubic phase bilayer, yielding a dimeric α-helical structure that is in excellent agreement with previously reported NMR measurements ...

Structure-function relationships of biological macromolecules, in particular proteins, provide crucial insights for fundamental biochemistry, medical research and early drug discovery. However, ...

First discovered in 2001, the protein PINK1 has been directly linked to Parkinson ... researchers from the Walter and Eliza Hall Institute of Medical Research (WEHI) have determined the structure of ...