Unexplained itching with no visible rash is more common than you think. Learn how your brain and nerves play a role in the ...

Nerve or neuropathic pain has long been a tricky condition to treat effectively. However, a new study has comprehensively ...

IDO1 and PDL1 are immune checkpoints with key roles in immune system regulation. Their relevance stems from their ability to suppress T-cell function. T-cells are vital to the body’s immune response ...

Researchers at the National Institutes of Health (NIH) have discovered clues as to how our bodies turn sensations such as ...

This valuable study combines real-time keypoint tracking with transdermal activation of sensory neurons to investigate sensory neuron recruitment in freely moving mice, and builds on the authors' ...

Each nerve cell has branches that stick out. They’re covered with proteins called receptors. A nerve cell uses those receptors to catch messages from other nerve cells. Then the nerve cell uses ...

The needles used in acupuncture are tiny, but they pierce the skin, creating microchannels. This stimulates nerve receptors and prompts the release of endorphins. Acupuncture has also been reported to ...

This stimulates nerve receptors and prompts the release of endorphins. Acupuncture has also been reported to reduce symptoms like headaches and popping and clicking in the jaw. Harriett Hargreaves ...

The development of the anti-migraine therapeutics, triptans-5-HT 1B/1D receptor agonists, had originally targeted the craniovasculature to exert therapeutic effects, and this locus of action ...

It starts with pain receptors in the affected area, called nociceptors, which send an “Uh-oh” message up the spinal cord to the brain. The brain opens and evaluates the DM, then ...