Chromatin remodelling can result from covalent modification of histones by histone acetyltransferases, histone deacetylases, histone methyltransferases or kinases, and by ATP-dependent protein ...

Histone post-translational modifications are covalent modifications of histones ... for instance during transcription and chromatin remodelling processes. The epigenetic and transcriptional ...

Artificial light, once a luxury, has become central to modern life, with its evolution spanning from fire to LEDs. Now, ...

Florida Governor Ron DeSantis wrote on X, formerly Twitter, on April 2: "I support the bill by Senator @IleanaGarciaUSA to ban geoengineering and weather modification. The Florida house ...

We collaborate with the world's leading lawyers to deliver news tailored for you. Sign Up for any (or all) of our 25+ Newsletters. Some states have laws and ethical rules regarding solicitation ...

The success of multiple covalent drugs against proteins once deemed “undruggable” has fueled growing interest in electrophiles that covalently bind amino acids such as cysteine. However, current ...

They noticed unapproved changes had been made to the rear attenuator, a safety device designed to absorb and reduce the force of impacts, and the assumption was the modifications would have given ...

in covalent targeting of lysine and tyrosine residues in cellular proteomes using electrophilic small molecules. Methods involving the use of photo-, enzyme-, and transition metal-catalyzed ...