Covalent modifications of histones are central to the regulation of chromatin dynamics, and, therefore, many biological processes involving chromatin, such as replication, repair, transcription ...

It has been suggested that the 'code' of covalent chromatin modifications is highly redundant 109. Some of this apparent redundancy may actually be instances of multivalent recognition where not ...

Chromatin modification is achieved by covalent histone modifications and nucleosome modifications. Histone acetylation, deacetylation, methylation, and phosphorylation are forms of covalent ...

They are the major protein component of chromatin and can undergo several covalent chemical modifications, including methylation, acetylation, phosphorylation, ubiquitylation, and sumoylation.

The basic mechanism of chromatin remodeling depends on the three dynamic properties of nucleosomes: reconstruction, enzyme-induced covalent modification, and repositioning. Regarding ...

Epigenetic regulation of gene expression is mediated through alterations in the DNA methylation status, covalent modifications of core nucleosomal ... and clinical development of epigenetic and ...

Covalent organic frameworks (COFs), possessing ... of the Chinese Academy of Sciences has proposed a multilevel post-synthetic modification strategy to construct catalytic COFs towards CO 2 ...