An interdisciplinary research team from Leipzig University and the Saxon AI center ScaDS.AI has developed a novel approach ...

Recent advances in automated protein design algorithms are leading a resurgence ... We have only just begun to scratch the surface of computational protein engineering, and much remains to be ...

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...

Researchers led by Truong Son Hy, Ph.D., from the University of Alabama at Birmingham, offer a simplified method they call ...

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.

As an assistant professor in the department ... in Chemistry was partly awarded to a pioneer in the field of computational ...

Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...

While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and design today were ... University of ...

Sneha Khedkar is an Assistant Editor at The Scientist ... 1 It served as a proof-of-concept that computational protein design was feasible. Despite the success of the Rosetta software, the accuracy of ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation. Various approaches ...