In a discovery three decades in the making, scientists at Rutgers and Brookhaven National Laboratory have acquired detailed ...

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Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in ...

Creating artificial enzymes typically requires either cofactors or complex structural arrangements that precisely position reactive groups in three-dimensional space. These requirements constrain ...

Subsequent numerical studies show that adenyl cofactors consistently influence the responsiveness ... the total concentration of each metabolic enzyme is constant while the substrate-level regulations ...

The structure of HemN reveals the cofactor geometry required for Radical SAM catalysis and sets the stage for the development of inhibitors with antibacterial function due to the uniquely bacterial ...

SAN RAFAEL, Calif. and BOSTON, May 16, 2025 /PRNewswire/ -- BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) and Inozyme Pharma, Inc. (Nasdaq: INZY) announced today that BioMarin has entered into a ...

“Without efficient cofactor recycling, high TTNs become economically unsustainable. For instance, unspecific peroxygenase (UPO) from Agrocybe aegerita maintains cost-effective large-scale ...

Researchers have developed a new workflow for designing enzymes from scratch ... and it becomes possible to use a variety of cofactors, including those that are not found in nature, to further ...

Researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch ... to use a variety of cofactors, including those that ...

Above-average temperature are forecast for the UK this weekend before thunderstorms hit parts of the country on Sunday, the Met Office has said. Much of the UK will enjoy blue skies on Saturday before ...

Researchers in the United Kingdom identified an enzyme, which they called Pap1, in a strain of Pseudomonas aeruginosa isolated from a wound. They found that the enzyme can break down a plastic ...