Thus, in her experiments, McClintock observed several fundamental properties of chromosome biology ... Only one extension cycle is illustrated in this figure, but in reality, telomerase is ...

Yet another critical cell cycle checkpoint takes place mid-mitosis. This check determines whether the chromosomes in the cell have properly attached to the spindle, or the network of microtubules ...

A mechanosensitive nuclear checkpoint triggers cell cycle arrest after chromosome mis-segregation. Chromosome segregation errors during mitosis, induced for example by centromere dysfunction (the red ...