Gotoh, E., Asakawa, Y. and Kosaka, H. (1995) Inhibition of Protein Serine/Threonine Phosphatases Directly Induces Premature Chromosome Condensation in Mammalian Somatic Cells. Biomedical Research, 16, ...

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such ...

Japanese researchers have successfully eliminated the extra chromosome responsible for Down syndrome using CRISPR gene editing.

Researchers from the University of Arizona have unveiled that coordinated Y chromosome loss in both cancer cells and immune cells may explain the worse prognosis in people with this alteration. The ...

The upcoming cycle supports a broad spectrum of grant programs, including early-stage basic research, translational efforts, clinical trials and manufacturing support. Maryland-based academic ...

"Every single cell can have a different chromosome structure," Cheng, a Curators' Distinguished Professor of Electrical Engineering and Computer Science, said.

Conclusions: Amivantamab downregulates EGFR and cell cycle pathways and increases cytotoxic immune cell signatures consistent with immune cell infiltration into tumors. Elevated AREG and EREG ligand ...

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy.

Mammalian condensed chromosomes exhibit diverse structural properties, as reflected in their varying stiffness across different cell stages and with aging.

The chromosome condensation and decondensation occur during the cell cycle [10]. Therefore, the chromosomes in different cell cycles have different shapes and sizes.

In a new study, researchers found that the inflammation behind painful episodes in sickle cell disease are correlated with the menstrual cycle.