Their results provide a novel insight into mitotic chromosome condensation in living human cells. Their work is published in the journal Proceedings of the National Academy of Sciences (PNAS ...

Mitotic chromosome condensation has fascinated biologists since Flemming's early illustrations of mitosis in the late nineteenth century. Now — 130 years later — chromatid condensation is ...

However, removal of scaffold proteins has no effect on chromosome condensation, suggesting that another factor causes the organization of metaphase chromosomes. Now, work led by Osaka University ...

A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. These have to be copied and distributed equally into two daughter cells at every division. Condensation ...

Therefore, the condensation of chromosomes is essential to accurately transmitting genetic information. A research team led by Professor Changyong Song and Dr. Daeho Sung, and Professor Jae-Hyung Jeon ...

This moment occurs in the last step of the cell cycle, the mitosis phase, where chromosomes condense, and fibrous structures called spindles form. Cohesin keeps the sisters properly glued until it ...

During cell division, chromosomes begin to condense and remain so until the division is complete. A number of proteins in the cell control the condensation, but so too do free ions such as Mg 2+.

Their results provide a novel insight into mitotic chromosome condensation in living human cells. Their work is published in the journal Proceedings of the National Academy of Sciences on August ...

which is essential for DNA condensation. We have also argued that unlinking of the sister chromosomes during DNA replication is aided by removal of pre-catenanes that are forming directly at or just ...