They had also evolved a nanobody (a small antibody-like protein) that responds to DNA damage ... More information: Alexander J. Cole et al, A chimeric viral platform for directed evolution in ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by ...

Ronald Levy, Stanford University With this technology, IDEC Pharmaceuticals researchers identified a hybridoma (2B8) that recognized CD20 and then developed a chimeric antibody (C2B8). This chimeric ...

Transgenic mice allow researchers to create “humanized” mice with human equivalents of murine antibody-coding genes. High throughput production of chimeric antibodies with murine-constant regions and ...

How do antibody engineers select isotypes? IgG1 has been the most popular choice by far and was used for 13 approved chimeric, humanized or fully human antibodies (compared with only two instances ...

South Korea-based DAAN Biotherapeutics has entered a licensing agreement with GC Cell, granting the latter exclusive rights to leverage its antibody sequence in the chimeric antigen receptor T ...

An international team of researchers co-led by UVA's Hui Li, PhD, looked at what are known as "chimeric RNA" in Chinese men and found both similarities and differences to those seen in Western men.

An ICMR-funded trial led by CMC Vellore demonstrated that CAR-T therapy, which uses a patient’s own T cells to fight cancer, can be safely manufactured at the hospital and infused to treat patients in ...

a fully human anti-VEGF monoclonal antibody; HALPRYZA, a recombinant chimeric murine/human anti-CD20 monoclonal antibody; SULINNO, a fully human antiTNF-a monoclonal antibody; Pemazyre ...