Direct chemical synthesis has been adapted to make oligonucleotides of remarkable length, including an 800 nucleotide green ...

The nucleosides are rich in exposed hydroxyl and amino groups, so scientists use protecting groups to prevent unintended reactions with compounds used in DNA synthesis. Chemicals remove the protecting ...

The method was developed by Frederick Sanger in 1975, who was later awarded the Nobel Prize in chemistry ... the DNA to be sequenced serves as a template for DNA synthesis. A DNA primer is ...

Figure 1: Chemical synthesis and theories of structure ... Initial attention has focused on preventing commercial DNA synthesis companies from supplying pathogenic or otherwise dangerous sequences ...

So how does protein synthesis make hair? If you've looked at the activity (or even the text version of the activity), you know how a section of DNA instructs a cell how to make a protein.

This breakthrough in enzymatic DNA synthesis overcomes traditional chemical synthesis limitations, offering researchers enhanced capabilities for applications such as mRNA vaccine development, ...

Chemical biology: development of novel molecular probes for DNA sequencing analysis and disease gene discovery Medicinal chemistry: development of new imaging and therapeutic agents towards cancer and ...

Chemical synthesis methods include the cyclization of urea with β-aminoacrylonitrile or the hydrolysis of 2-amino-4,6-dichloropyrimidine. Cytosine can also be isolated from DNA or RNA through ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...

Their team has made great strides in designing and developing an enzymatic DNA synthesis platform with exciting technical advantages over traditional chemical synthesis,” said Trey Martin ...