A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...

G beta-gamma (purple circles), and a G-protein-coupled receptor (GPCR; light green loops). Upon receptor stimulation by a ligand called an agonist, the state of the receptor changes. G alpha ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

HHMI’s Robert Lefkowitz shares prize with Brian Kobilka for research on G-protein coupled receptors. The Royal Swedish Academy of Sciences announced today that Robert J. Lefkowitz, a Howard Hughes ...

Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes ...

Dublin, May 06, 2025 (GLOBE NEWSWIRE) -- The "G-Protein Coupled Receptor (GPCR) Targeting: Technologies and Global Markets" report has been added to ResearchAndMarkets.com's offering. The global G ...